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The outcome of modafinil on cortical glutamate is unclear, as it has been noted that modafinil improves cortical glutamate Which modafinil won't appreciably raise cortical glutamate (Pierard et al 1995; Bettendorf et al 1996). The chance that modafinil alters GABA and glutamate synthesis costs was explored as is possible explanation of modafinil’